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CHOice®

In-house solution for CHO clone selection

Cergentis kit CHO clone selection
 

Accelerating time to clinic by de-risking clone selection early in the CHO cell line development process

 

In addition to Cergentis' TLA-based services for Chinese Hamster Ovary (CHO) clone selection, we now offer
a new in-house solution: CHOice®.
This allows our customers to access the same high-quality results while profiting from even shorter turnaround times, cost-efficiency, scalability and confidentiality.  

cell line development process

CHO clone selection

Selecting the clone with the preferred genetic make-up is a crucial step in the cell line development process toward producing stable and high-quality biotherapeutic proteins. Cergentis' TLA-based services have a proven track record in the genetic QC and characterization of cell lines and in clone selection. Conventional technologies are limited when it comes to sensitivity, cost and turnaround time. Our TLA-based analysis yields all essential genetic characteristics in a single test: an ideal platform to monitor important quality parameters for clone selection. 

 

 Identifying siblings
Deselecting clones containing undesired mutations in the coding sequence of GOI
De-risking clones early in the cell line development proces
Accelerating timelines 
 Facilitating early phase testing
Minimizing time to clinic

Your CHOice®

The in-house solution for CHO clone selection combines the widely-published and recognized TLA analysis with our newly developed software platform. 

 

   Integrated solution from sample processing up to analysis

   More cost effective than outsourcing and at larger throughput

   Reduced turnaround time (7 - 14 days from sample to results)

   Master your own data and materials

   User friendly and independent of Cergentis' capacity

   Highly scalable

   Automated, unbiased data analysis

   Highest quality standard

Lab_ge
kit CHO clone selection

Fully integrated solution, starting from €9,900

The fully integrated in-house solution CHOice® comprises of the following:

 

 Reagents kit for 12 samples

 User manual

 Access to Cergentis' software analysis platform
 Customer & tech support
 Expert consultation
 Orderable controls

* First time users will undergo a qualification trajectory including both wetlab and data analysis training.

Our TLA-based services for cell line development & clone selection

What our customers say

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"TLA analysis has proven to be very useful to quality control genetically engineered cell lines.”

 

 

 

 

Dr. John Wiseman

Associate Director - AstraZeneca

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"Working with the team at Cergentis has allowed us to add an extra dimension to the analysis of our stable cell lines. Their understanding of our needs combined with the reliability and reproducibility of TLA analysis has resulted in a number of successful projects."

 

Dr. Teresa Domagala

Director Manufacturing Dev. - Teva

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"TLA outperforms traditional methods used in CHO cell line characterisation and provides higher resolution and sensitivity.”

 

 

 

Dr. Stefanie Bartels

Project Leader CLD - Byondis

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